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Creatine for brain health & physical performance | Dr Eric Rawson

The Proof with Simon Hill

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Is There a Down Regulation of Transporters in Creatine?

Once you supersaturate your muscles, they're stuck there and it's going to take you a few weeks for everything to get back down to normal. With creatine because this is a nutrient, I don't see a reason to cycle. If my body decreases endogenous synthesis because my muscles are 20% above what they are without the supplement, then I'm okay with that. And if you look at urinary creatinine levels over time when people are washing out with the supplement, so to speak, it appears that everything returns.

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