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Ep. 294: “HSC Development and Regulation” Featuring Dr. Margaret Goodell

The Stem Cell Podcast

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Advancements in Brain and Liver Organoids

This chapter examines the intricate processes of brain development through the lens of morphogen gradients and the introduction of a dual orthogonal morphogen-assisted patterning system, DUOMAPS, for enhanced organoid manipulation. It also discusses the promising development of adult human hepatocyte organoids, focusing on their potential for disease modeling and therapeutic applications in liver diseases. The dialogue underscores both the advancements and challenges inherent in stem cell research, particularly in achieving consistency and optimization in organoid growth.

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