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Alessio Ciulli: At the Forefront of Targeted Protein Degradation

Back of the Napkin - Inspiring Stories from Biotech Pioneers

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Introduction to Pro Tacks: Harnessing Ubiquitin Proteasome System for Targeted Protein Degradation

This chapter provides an overview of targeted protein degradation using pro tacks, which connect with a different protein involved in the ubiquitin proteasome system to mark the target protein for degradation. It discusses how pro tacks work and their advantages over conventional drugs.

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