TWiV 1187: The tau of herpesvirus
This Week in Virology
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C-Gas Pathway and Alzheimer's Disease
This chapter explores the C-Gas signaling pathway's connection to herpes viruses and its implications in Alzheimer's disease. It highlights the roles of TBK1 kinase and transcription factors like NF-kappa B in tau phosphorylation and immune responses, particularly in advanced Alzheimer's cases. The discussion raises questions about tau's function as an immune response element and its interaction with various viral infections, underlining the complexities of Alzheimer's research.
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