There is shockingly little long term evidence into chemicalanty depressens. The best research we have is called the star de trils. Most people giving chemiclanty depressents do become depressed. That doesn't tell me there's no value in these drugs, but it tells you we need to have a much wider menu of options.
Author and journalist Johann Hari talks about his book, Lost Connections: Why You Are Depressed and How to Find Hope, with EconTalk host Russ Roberts. Hari, who has suffered with depression as a teenager and an adult, offers a sweeping critique of the medical establishment's understanding of depression and the frequent reliance on pharmaceutical treatments. Hari argues that it is our lost connections with each other, with our work, and with ourselves that explains the rise in depression in recent times.