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Gene therapy won't be suitable for everyone, because known gene mutations determine only a small proportion of cases of Alzheimer's. The company AlcaHest has completed a small clinical trial testing whether factors in the blood of young people could replace those lost in the aging process. Most researchers think that treatment will need to be personalised. Those at different disease stages will need different therapies. It is too early to say which, if any of these potential new therapies will pan out.