Exploring Immune Dynamics and Germinal Centers

This chapter examines the historical and modern contributions to immunology, particularly in understanding IgA secreting plasma cells and their interactions within mucosal tissues. It explores advanced mouse models that visualize T and B cell behaviors, focusing on germinal center activities and immune responses in lymphoid structures. The discussion emphasizes the complexity of immune dynamics shaped by both natural and induced stimuli, including the significant role of commensal microbes and the implications for vaccine strategies.