18min chapter

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How Placebo Effects Work to Change Our Biology & Psychology

Huberman Lab

CHAPTER

The Influence of Mindset on Physiological Responses

This chapter explores various studies showcasing how beliefs and perceptions impact hormonal responses, exercise benefits, and stress responses. It delves into the intricate neural pathways connecting the prefrontal cortex to the hypothalamus and brainstem, influencing physiological changes during stressful situations and placebo effects. Additionally, the role of genes like COMT in modulating the magnitude of placebo effects through dopamine, norepinephrine, and epinephrine regulation is discussed.

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