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“AAI 2022: Peritoneal Macrophages” Featuring Dr. Gwendalyn Randolph

The Immunology Podcast

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The Complex Relationship Between Macrophages, Lipids, and Immune Functions

This chapter explores the intricate connection between macrophages and lipids, discussing how macrophages store lipids as a protective mechanism against toxicity and the role of scavenger receptors in lipid uptake. It delves into the diverse functions of macrophages in processes like atherosclerosis and highlights the differentiation of monocytes into macrophages in different environments, emphasizing the need to categorize tissue macrophages based on their origins and functions rather than solely on traditional M1 and M2 classifications.

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