The Effects of Bempedoic Acid on Cholesterol and Cardiovascular Health

Bempedoic acid is a therapeutic agent that works upstream of the HMG coiraductase. In this study 13,970 subjects who had either known atherosclerotic cardiovascular disease or went high risk were randomizedeither to receive bempedoic acid or a placebo. It lowered LDL cholesterol by about 21.1 at six months compared with a.8 reduction in placebo. So bempedaic acid seems to have impact analogous to a moderate intensity statin and could present a significant alternative to individuals who are intolerant of taking statin therapy.