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December 2024 Recall: Topics in Autoimmune Neurology

Neurology® Podcast

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Understanding NMOSD: Risks and Prognosis

This chapter explores the pathology and clinical features of aquaporin-4 positive neuromyelitis optica spectrum disorder (NMOSD), emphasizing the impact of autoantibodies on patient outcomes. It highlights a nationwide cohort study from Denmark revealing significantly reduced life expectancy and the critical factors influencing mortality. Additionally, it addresses the importance of accurate diagnoses and mental health support for affected individuals, comparing NMOSD with multiple sclerosis regarding mortality rates.

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