Ralston College presents a lecture delivered on October 26th, 2021 by Dr Iain McGilchrist followed by a discussion with Dr Stephen Blackwood and questions from the audience. In his lecture Dr McGilchrist deals with certain themes that are treated at greater length in his recent book The Matter With Things. He focuses especially upon the coincidence of opposites (coincidentia oppositorum), which he explores (providing an extraordinary range of illustrative examples) in such a way as to make manifest both its universality and its particular relevance to our present historical moment.