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Diagnosis and Management of Patients With Prediabetes

JAMA Clinical Reviews

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The Benefits of Lifestyle Interventions for Diabetes Prevention

Lifestyle interventions work and in your review you also talked about medication use highlighting the use of metformin. Tell us how those lifestyle interventions actually work in terms of the outcomes. Lifestyle intervention needs to be the foundation, the platform upon which we consider intensification with any medication. So whilst we do not recommend medications as the first line approach, we do recognize that metformin may be particularly appropriate for certain individuals.

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