2min chapter

The TED Interview cover image

The science and ethics of rewriting our DNA | Jennifer Doudna

The TED Interview

CHAPTER

Can Crisper Really Edit Cells in Animal Models of Genetic Disease?

In em ancan can crisper actually live edit in a living adult like millions and millions of different cells, enough to effect the kind of biological impact that that revised dna would need to change our biology? Ah, yes. Great question. So one of the things that's very interesting about crisper is that we're already learning in various animal models of genetic disease that in many cases, first of all, it's not necessary to edit the d na every cell in the animal to have a therapeutic benefit. And secondly, in many cases, you only need to edit cells in one kind of tissue. Maybe you only need to get to the liver or the brain, or the heart or

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