
34. Psilocybin vs Antidepressants with Dr Robin Carhart-Harris
The Drug Science Podcast
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Psilocybin and Depression: A Different Mode of Action
Psilocybin was used to treat depression in patients who had taken 11 different medications. Brain imaging suggested perhaps a slightly different mode of action to conventional antidepressants, isn't it? Yes, yes. We saw these curious anomalous increases in amygdala. This emotion center in the brain is sensitive to emotional stimuli.
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