Gene Sequencing - What Do We Want to Know?

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i'm concerned that people not make one of two mistakes when they get their dna sequenced. One mistake is to be like sor angry and irritated that they didn't find anything in their genom. I mean, i have plenty of jeans that have been associated with raising my risk of this disease or that by some modest amount. But th doesn't mean that i'm going to die of any of those diseases. You don't h verything that really jumps out, you know, is what they would say. There's nothing where it's like, hey, that jean, that's big trouble.

Our understanding of heredity and genetics is improving at blinding speed. It was only in the year 2000 that scientists obtained the first rough map of the human genome: 3 billion base pairs of DNA with about 20,000 functional genes. Today, you can send a bit of your DNA to companies such as 23andMe and get a report on your personal genome (ancestry, health risks) for about $200. Technologies like CRISPR are allowing scientists to edit genes, not just map them. Science writer Carl Zimmer has been following these advances for years, and has recently written a comprehensive book about heredity: She Has Her Mother's Laugh: The Powers, Perversions, and Potential of Heredity. We talk about how our understanding of heredity has changed over the years, how there is much more to inheritance than simply listing all the information we pass down in our DNA, and what the future might hold in a world where genetic manipulation becomes widespread. [smart_track_player url="http://traffic.libsyn.com/seancarroll/carl-zimmer.mp3" social_gplus="false" social_linkedin="true" social_email="true" hashtag="mindscapepodcast" ] Carl Zimmer is a leading science writer whose work regularly appears in The New York Times, National Geographic, The Atlantic, and elsewhere. He is the author of thirteen books, including a university-level textbook on evolutionary biology. He has been awarded prizes and fellowships by the National Academy of Science, the American Association for the Advancement of Science, and the Guggenheim Foundation, among others. He teaches as an adjunct professor at Yale University. Home page Matter column in The New York Times Yale home page Wikipedia page Amazon author page Talk on Science, Journalism, and Democracy Twitter Download Episode See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.