The Benefits and Limitations of Folic Acid Supplementation for Pregnancy

The U.S preventive service task force reaffirmed its 2017 recommendation that all people who plan to or could become pregnant take daily supplementation of 400 to 800 milligrams of folic acid. Joan Morris and Nicholas Wald discussed why folate deficiency resulting in neural tube defects remains an important and preventable public health issue worldwide. A JAMA clinical challenge describes the case of an older patient with history of surgical decompression for syringomyelia, poor mobility, and frequent falls.