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TWiN 7: Stress, the good, bad and beautiful

This Week in Neuroscience

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Dred and GQ Signaling in the Presence of CNO in the Sympathetic Nerves

Dred is a receptor that doesn't activate does not activate by any endogenous ligands so nothing in the body is going to activate it. And what they've done here is they've expressed a Dred that leads to GQ signaling in the presence of CNO in the sympathetic nerves and show that just giving CNO mice that are expressing the Dred can lead to grain in the absence of stress. So this yes this is a new technique or a relatively new technique that I think is also super cool I think it's on par with off to genetics but I mean I just want to explain how it works because you're using a signaling cascade from a receptor which is something that the cell uses

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