ACR24 - SPONDYLOARTHRITIS
Rheumnow Podcast
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Navigating Treatment-Resistant Axial Spondyloarthritis
This chapter explores the effectiveness of TNF and IL-17 inhibitors in patients who have not responded to initial TNF therapy, revealing that TNF inhibitors, while more effective, pose greater safety risks. It also introduces a new ASAS consensus definition for difficult-to-manage axial spondyloarthritis, emphasizing the need for objective measures to diagnose treatment-refractory patients. The discussion highlights the role of sex-related differences in treatment responses and recent advancements in classification criteria and predictive technologies.
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