CPX351 vs 3-0-7 in Patients With MDS Type Mutations

The major confusion or clinical dilemma is whether to use A's and VAN or CPX351 in patients with bad prognosis. Linearly did a post hoc analysis of the CPX versus 3-0-7 paper and showed that people with P53 didn't benefit from CPX compared to 3-0/7. So you might as well use phonetic laxa so if a P53 is still a bugaboo but there may be a subset of patients who have don't have CPX351 eligible phenotype or genotype which would make them eligible for it.