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Episode 24. ASCO/EHA 2023 Special: Updates on CAR T-cell Therapy in Myeloma

Blood Cancer Talks

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Cerebellar Toxicity in GPRC 5D CAR-T

Cerebellar toxicity was seen in two patients receiving the 450 million dose. It's possible that they're able to find a dose where you get an efficacy and maybe a lower risk of this cerebellum toxicity. So, I don't know if it's going to be a major barrier. I think we'll have to wait and see as we treat more numbers. My hope, though, is that this is something that's very uncommon and won't be a barrier.

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