
TWiV 1209: Just say no to norovirus
This Week in Virology
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Vaccine Trials and Immune Responses in Older Adults
This chapter discusses a study on a vaccine and placebo trial involving older adults, focusing on safety, tolerability, and common adverse events. It explores the antibody responses to norovirus vaccination, emphasizing the unexpected immune responses in older individuals and the role of mucosal immunity. The speakers also reflect on the dynamics of placebo-controlled trials, share personal anecdotes, and highlight the need for further research on vaccine efficacy.
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