2min chapter

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How To Man Up About Male Birth Control

How To!

CHAPTER

Innovations in Male Birth Control: Hormonal Gel Development

This chapter explores a groundbreaking hormonal gel designed for male contraception, combining testosterone with nestorone to regulate sperm production. It discusses current clinical trials and the future of male birth control, addressing both advancements and challenges in the field.

00:00
Speaker 2
Can you talk a little bit about your work in that area and what being developed and what is under development and what the future of that might look like absolutely
Speaker 3
my work with the male conscious clinical trials network is work on a hormonal gel a combined hormonal gel that combines both testosterone and a progestin called nestorone and similar to female hormonal contraceptives, the goal is to have that drug be absorbed by the system and it will create signals in the brain and the pituitary to basically block the signaling to the testes, which will stop the testes from producing testosterone and sperm. Note again that while we're stopping testosterone from being produced in the testes, we're also giving it back systemically. And so testosterone levels should remain normal. Hormonal methods for men had been investigated for a long, long time, not too long after the advent of female hormonal contraceptives. The issue was figuring out how to give men testosterone. We actually found that when administered as a gel, you could actually reach a level that was sufficient without being toxic to the body. clinical trial is aimed at making sure that it works, right? So we had more than 200 couples who use this gel for over a year as their sole method of contraception and nothing else. I can't tell you the full results yet, but we're pretty pleased. And we are currently in the process of getting a phase three trial funded. Excellent.
Speaker 2
Are there other methods that are underway that are in process?

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