Irritable bowel syndrome (IBS) is often diagnosed when symptoms don’t have an obvious cause. But anyone with IBS symptoms knows it’s a REAL condition. Dr. Alex Ford and I are share what irritable bowel syndrome treatments are getting wrong—and how to start feeling better.

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Timestamps

00:00 Intro

04:40 What is IBS?

12:00 The problem with restrictive diets

14:35 Prevalence of SIBO in IBS patients

21:06 The gut-brain connection

25:25 Antidepressant effects on the gut

33:30 Do probiotics work for IBS?

40:28 IBS symptoms

47:06 Treatment options

Featured Studies

Ford’s Research

📉Efficacy of Probiotics in IBS: https://pubmed.ncbi.nlm.nih.gov/37541528/

📉Antibiotics and Probiotics for IBS: https://pubmed.ncbi.nlm.nih.gov/37184752/

📉Amitriptyline at Low-Dose and Titrated for IBS as Second-Line Treatment in primary care: https://pubmed.ncbi.nlm.nih.gov/37858323/

📉Disorders of gut-brain interaction: https://pubmed.ncbi.nlm.nih.gov/35781806/

📉Rome IV Criteria: https://theromefoundation.org/rome-iv/rome-iv-criteria/

📉Global prevalence of IBS according to Rome III or IV criteria: https://pubmed.ncbi.nlm.nih.gov/32702295/

📉IBS and the Gut Microbiome: A Review: https://pubmed.ncbi.nlm.nih.gov/37048642/

📉Lactobacillus acidophilus NCFM affects colonic mucosal opioid receptor expression: https://pubmed.ncbi.nlm.nih.gov/24853043/

📉Interactions between symptoms and psychological status in IBS: https://pubmed.ncbi.nlm.nih.gov/36178333/

📉Probiotics fortify intestinal barrier function: https://pubmed.ncbi.nlm.nih.gov/37168869/

📉Probiotics for Preventing and Treating SIBO: https://pubmed.ncbi.nlm.nih.gov/28267052/

📉The effects of probiotics on constipation in adults: https://pubmed.ncbi.nlm.nih.gov/32005532/

📉The effect of multistrain probiotics on constipation in the elderly: https://pubmed.ncbi.nlm.nih.gov/35927504/

📉Efficacy of probiotics, prebiotics and synbiotics in IBS: https://pubmed.ncbi.nlm.nih.gov/37772692/

📉Outcome-Specific Efficacy of Different Probiotic Strains in IBS: https://pubmed.ncbi.nlm.nih.gov/37686889/

📉Strain-specific and outcome-specific efficacy of probiotics for IBS: https://pubmed.ncbi.nlm.nih.gov/34712929/

📉Efficacy of probiotics, prebiotics and synbiotics in IBS: https://pubmed.ncbi.nlm.nih.gov/37772692/

📉Efficacy of a low FODMAP diet in IBS: https://pubmed.ncbi.nlm.nih.gov/34376515/

📉Dietary glutamine supplements for post infectious IBS: https://pubmed.ncbi.nlm.nih.gov/30108163/

📉Peppermint oil for IBS: https://pubmed.ncbi.nlm.nih.gov/24100754/

📉Efficacy and Safety of Peppermint Oil in [...] Patients With IBS: https://pubmed.ncbi.nlm.nih.gov/31470006/

📉The IBS Outcome Study (IBSOS): https://pubmed.ncbi.nlm.nih.gov/22846389/

📉Treatments for diarrhea-predominant IBS: https://pubmed.ncbi.nlm.nih.gov/30194692/

📉Comparing probiotic and drug interventions in IBS: https://pubmed.ncbi.nlm.nih.gov/35848115/

📉Probiotics, prebiotics, and low FODMAP diet for IBS: https://pubmed.ncbi.nlm.nih.gov/30935559/

📉Anti-inflammatory effect of amitriptyline in a rat model of acetic acid-induced colitis: the involvement of the TLR4/NF-kB signaling pathway: https://pubmed.ncbi.nlm.nih.gov/33336463/

📉An Investigation on in vitro and in vivo Antimicrobial Properties of the Antidepressant: Amitriptyline Hydrochloride: https://pubmed.ncbi.nlm.nih.gov/24031539/

📉Amitriptyline modifies the visceral hypersensitivity response to acute stress in the IBS: https://pubmed.ncbi.nlm.nih.gov/19076934/

📉Effect of a tricyclic antidepressant on small intestinal motility in health and diarrhea-predominant IBS: https://pubmed.ncbi.nlm.nih.gov/7821126/

📉Recurrence of depression after discontinuation of long-term amitriptyline treatment: https://pubmed.ncbi.nlm.nih.gov/6800270/

📉Long-term amitriptyline in chronic depression: https://pubmed.ncbi.nlm.nih.gov/3894196/

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DISCLAIMER: The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of your physician or other qualified healthcare provider before starting any new treatment or discontinuing an existing treatment.

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