Navigating Antibiotic Challenges in Critical Care

This chapter addresses the complexities of managing acute kidney injury and sepsis, with an emphasis on the critical importance of antibiotic dosing strategies. It examines the impact of beta-lactam dose adjustments on patient outcomes and discusses recent research on transitioning from IV to oral antibiotics, highlighting both successes and challenges. Additionally, the chapter explores stewardship practices, particularly in treating asymptomatic bacteriuria, underscoring the need for careful patient assessment to optimize antibiotic use.