When we say off, what is off really? Right. So in mental health profession, it's if you have a difference that's interfering with your ability to perform tasks in your personal or professional life then it's a difference that needs to be treated as abnormal. If you have too much dopamine, then you're probably not motivated to do anything because you've got everything that you need. In early experiments around the dopamineergic system, they allowed rodents to just self-administered stimulation to their dopamine like whenever they wanted. And it basically interrupted all functions except for sleep. But like people have probably experienced this before. You don't eat like your sleep's kind of disrupted. Your normal function

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