The Effects of Saturated Fats on the Gut Microbiome

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The study looked at mice on a high fat diet. The output was intestinal inflammation, so colitis. And we found first that it shifted the microbiome, that saturated fat specifically to a bloom of this bollophila,. So then we backtracked and said, why this bug? And if you look into the genetics of the bug, and what it does, it loves biol, biolophila. There must be something going on with the biolasic composition in response to this diet.

Episode #267. Join me for a deep dive into the influence of the gut microbiome on inflammation and metabolic disease. In this fascinating exchange with Dr Suzanne Devkota, we explore the role of the gut in these conditions, shedding light on food allergies, IBD, and obesity. You’ll learn the practical tips you need to nurture a healthy microbiome, as well as gain a better understanding of what we do – and don’t – know about this incredible system.

Specifically, we discuss:

Intro (00:00)
The evolving field of microbiome research (02:13)
Gut microbe on social media (09:32)
Microbiome definition (12:48)
Why the focus on gut bacteria? (13:55)
Differences in Microbes (16:02)
Microbial shifts and adaptations (18:45)
Microbes perturbations (21:35)
Human microbiome in evolution (23:54)
Healthy microbiome and diversity (27:47)
Is the microbiome the sole driver of metabolic diseases? (33:05)
Dietary patterns and FODMAP intolerance (41:07)
Saturated fat and gut health (49:15)
Microbiome metabolites and heart disease risk (57:42)
Inflammatory bowel disease (IBD) and dysbiosis (1:02:09)
Food additives (1:12:29)
Supporting the microbiome in IBD (1:15:29)
Microbiome's interaction with fat cells (1:16:52)
Short-chain fatty acids and appetite regulation (1:29:26)
Practical tips for nourishing a healthy gut (1:31:05)
Microbiome's interaction with Polyphenols (1:38:43)
On supplements and fermented foods (1:39:15)
Factors affecting gut health beyond nutrition (1:46:22)
Outro (1:50:10)

Connect with Dr Suzanne Devkota on Instagram and Twitter. Learn more about her research at http://www.devkotalab.com/thelab.

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Enjoy, friends.

Simon

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Simon Hill, MSc, BSc (Hons)

Creator of theproof.com and host of The Proof with Simon Hill

Author of The Proof is in the Plants

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