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There's a whole PEP about that (Changelog & Friends #5)
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The Pros and Cons of a Global Interpreter Lock for Python
Python uses reference counting for garbage collection. The problem is if you put a little lock on every single object, your performance sucks. It's been looked at over the years and people have never been able to find a way historically where we could get rid of that global interpreter lock. But it does allow scaling with threads to number of cores roughly.
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