3min chapter

Huberman Lab cover image

How to Optimize Fertility in Males & Females

Huberman Lab

CHAPTER

Is There a Positive Feedback Loop on the Pituitary?

The pituitary can release things like follicle stimulating hormone and luteinizing hormone. It's going to go into the bloodstream and it's going to travel back to the pituitary. In females, when estrogen is relatively low, but not zero, during that first follicular half of the ovulatory cycle, it actually triggers negative feedback on LH and FSH so that not too much is produced. But then just prior to ovulation, the levels of estrogen and the levels of some other hormones from those eggs gets high enough that it actually triggers a positive feedback loop on the pituitsary. That deployment or the release of that one mature, proper selected egg with the 23 individual

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