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The Immorality of Consent
Human flourishing can be conceived as broadly as you want, and emits a definition tat is continually open for refinement. It's immoral to close off the paths to correction of the theory it turns out to be false. The reason why knowledge trumps everything else here is falliblism. And who knows how far that can go, but we know it's possible to move in the wrong direction. We never want to tie our hands and make it impossible to correct course.