5min chapter

This Podcast Will Kill You cover image

Special Episode: Dr. Andrew Wehrman & The Contagion of Liberty

This Podcast Will Kill You

CHAPTER

The History of Inoculation

Inoculation is a much older practice than vaccination and differs from vaccination in some key ways that have these potential health consequences for a non-immune community. In 1721, when smallpox started breaking out in Boston, Mather wrote a letter to all the doctors in Boston saying, now's the time to do it. The disease spreads almost 6,000 people in Boston which was nearly half the population gets infected. About 15% of the people in Boston in 1721 who are infected die.

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