
Audio long read: She was convicted of killing her four children. Could a gene mutation set her free?
Nature Podcast
The Folbig Mutation Impairs Calcium Channels
Folbig mutation known as G114R impairs how calmodulin attaches to two crucial channels that control the movement of calcium into the cell. The combined effect of the variant on both channels will increase calcium in the cell, which increases the chance of a arrhythmia. In November 2020, the international team published its findings in the journal EP Europace.
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