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The Drake Equation Is Enlightening
We already know there is a crap ton of planets out there that are Earth-like and we also know that most of them do not seem to have anything like our kind of life on. So what went wrong? There's clearly one step along the evolutionary, at least one filter, roadblock, in going from no life to space-faring life. And where is it? Is it in front of us or is it behind us? If there's no filter behind us and we keep finding lots of little mice on Mars or whatever, that's actually very depressing because that makes it much more likely that the filter is in front of ourselves.