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Unleashing the Power of CAR T Cells: Efficacy and Challenges
This chapter explores the remarkable efficacy of CAR T cells in treating malignancies in B cells, showcasing their surveillance capabilities even post-remission. It delves into the challenges of hyperactivation of the immune system leading to cytokine storms, illustrated by cases like Emily Whitehead's treatment. Additionally, it discusses the evolution and commercial success of CAR-T cell therapy, emphasizing the hurdles in targeting solid tumors and the need for innovative approaches in enhancing T-cell function.