Dr Richard Johnson | Why it’s Fructose (NOT GLUCOSE) That Drives Insulin Resistance and Metabolic Disease KKP: 602
Metabolic Freedom With Ben Azadi
The Evolution of Uric Acid
Humans had a mutation in uric acid that allowed them to store more fat than other species. They mutated it so they got a bigger uric acid response, then when they got fructose they made a huge amount of fat for the same amount of fruit. When liver cells human liver cells had that gene, they made fat and response to fructose they did. And then we took mice and mice are fairly resistant to sugar, but when we knocked out that enzyme or inhibited it to make it kind of like a human then suddenly they were very sensitive to sugar. It's fascinating.
Today, I am blessed to have here with me Dr. Richard Johnson. He is a professor of medicine at the University of Colorado and is a clinician, educator, and researcher. He is board-certified in internal medicine, infectious diseases, and kidney disease and is the founding editor of Comprehensive Clinical Nephrology, one of the main textbooks on kidney disease.
90 Day Heavy Metals Detox Program: http://www.ketokampdetox.com (LIMITED SPOTS)
For more than 20 years, he has led research on the cause of obesity and diabetes, with a special interest in the role of sugar (especially fructose) and uric acid. His research has been highly cited, published in top medical journals, and supported by grants from the National Institutes of Health. He is the author of The Sugar Fix and The Fat Switch. Dr. Johnson lives in Colorado with his wife, kids, and two rambunctious puppies.
- Read Nature Wants Us To Be Fat: https://www.amazon.com/Nature-Wants-Fat-Prevent-Reverse-ebook/dp/B097XMY9VG/benazadi-20
In this episode, Dr. Johnson talks about the inspiration behind his uric acid research. He speaks about the correlation between uric acid, fructose, sugar, and inflammation. Plus, he explains why your body would be producing excess uric acid. Later, we discuss why the keto lifestyle is so powerful and the reason burning calories isn’t the purpose behind exercise. Tune in as we dive into the benefits of the ketogenic lifestyle and Dr. Johnson’s latest book, Nature Wants Us To Be Fat.
90 Day Detox Program: http://www.ketokampdetox.com
Order Keto Flex: http://www.ketoflexbook.com
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Biotiquest Sugar Shift product. Regulate glucose, reduce cravings, achieve deeper ketosis, and remove glyphaste. https://biotiquest.com/products/sugar-shift Use the coupon code KAMP10 for 10% off their products.
Get Bioptimizers Magnesium Breakthrough for the best night of sleep, ever! Nurture your mind and body with this all-natural, full-spectrum magnesium supplement. Visit www.magbreakthrough.com/ketokamp and use code ketokamp10 for 10% off.
Text me the words "Podcast" +1 (786) 364-5002 to be added to my contacts list.
[01:00] About Dr. Johnson and The Inspiration Behind His Research
- Johnson started studying high blood pressure because it’s such a problem in our country.
- High blood pressure has something to do with the kidneys and salt.
- A substance called uric acid seems to be important in what causes high blood pressure.
- As he studied uric acid, he started to realize it was more than just high blood pressure and gout.
- Uric acid is actually involved in obesity, metabolic syndrome, and diabetes.
- Eventually, he found that fructose led to an increase in uric acid.
[04:20] What Is The Connection Between High Uric Acid and Inflammation?
- Our body is made up of protein, carbohydrates, fat, bone, etc.
- Uric acid is considered a waste product.
- When we eat meats, drink beer, and eat sugar, these foods can generate uric acid.
- Uric acid is what is excreted from the body.
- If uric acid is built up, it can lead to inflammation and gout.
- 9 million people in the United States suffer from gout.
- A lot of people have low-grade inflammation in their blood. This inflammation can accelerate diseases like atherosclerosis and heart disease.
[09:10] Why Is Your Body Producing Excess Uric Acid?
- If your uric acid is very high, it increases your risk for mortality.
- Plus, uric acid is being linked to cancer.
- Uric acid is involved in the process to make fat.
- When you eat enough fructose, it triggers uric acid.
- The body switches from making a lot of ATP to storing the energy in fat.
- Uric acid is actually important in survival.
- Humans are very sensitive to fructose. Fructose is in table sugar and high fructose table sugar.
[24:20] Why The Keto Lifestyle Is So Powerful
- Our bodies can make fructose. Potatoes and rice do not contain fructose, but they contain what we call high glycemic carbs, it triggers this response in your body to make fructose.
- You will start making fructose in response to these carbs.
- That's why carbs are driving obesity dramatically.
- The keto diet is powerful because it blocks these two major food groups: fructose and high glycemic carbs.
[29:30] The Benefits You Get From Exercise
- When you exercise, you do things that help the mitochondria regenerate.
- If the mitochondria regenerate, they can go back to normal.
- When the function of the mitochondria improves, your energy improves.
- You can diet all you want, but if your mitochondria are bad, you will also go back to your original weight.
- When you’re young and gain weight, you can lose it much easier.
[38:55] One of the Many Benefits of A Ketogenic Lifestyle
- When you eat sugar, you have to absorb the sugar.
- The ability to absorb sugar varies from person to person.
- If you're eating sugar every day, you're going to absorb the sugar very fast.
- When you put an animal on a high sugar diet, it will learn how to absorb it fast and absorb it very efficiently.
- If you don't eat sugar, those transport systems to transport the sugar into the body get turned off.
[43:35] The Importance of Oxygen For Creating Energy
- When you make ATP in the mitochondria, you use oxygen.
- One of the main reasons we need oxygen is for our mitochondria to make the energy we need.
- If we don't have enough oxygen, we can't make energy very well.
- Our body likes to use glucose as fuel.
- Insulin resistance reduces the amount of glucose that gets into our muscles, liver, and fat.
- Much of the brain does not require insulin to move glucose in.
AND MUCH MORE!
Resources from this episode:
- Check out Dr. Johnson’s Website: https://drrichardjohnson.com/
- Follow Dr. Johnson
- Read Nature Wants Us To Be Fat: https://www.amazon.com/Nature-Wants-Fat-Prevent-Reverse-ebook/dp/B097XMY9VG/benazadi-20
- Get The Sugar Fix: The High-Fructose Fallout That Is Making You Fat and Sick: https://www.amazon.com/Sugar-Fix-High-Fructose-Fallout-Making-ebook/dp/B0017SWT5S/benazadi-20
- Get all of Dr. Johnson’s books: https://drrichardjohnson.com/books/
- Join theKeto Kamp Academy: https://ketokampacademy.com/7-day-trial-a
- WatchKeto Kamp on YouTube: https://www.youtube.com/channel/UCUh_MOM621MvpW_HLtfkLyQ
90 Day Detox Program: http://www.ketokampdetox.com
Order Keto Flex: http://www.ketoflexbook.com
--------------------------------------------------------
/ / E P I S O D E S P ON S O R S
Biotiquest Sugar Shift product. Regulate glucose, reduce cravings, achieve deeper ketosis, and remove glyphaste. https://biotiquest.com/products/sugar-shift Use the coupon code KAMP10 for 10% off their products.
Get Bioptimizers Magnesium Breakthrough for the best night of sleep, ever! Nurture your mind and body with this all-natural, full-spectrum magnesium supplement. Visit www.magbreakthrough.com/ketokamp and use code ketokamp10 for 10% off.
Text me the words "Podcast" +1 (786) 364-5002 to be added to my contacts list.
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Disclaimer: This podcast is for information purposes only. Statements and views expressed on this podcast are not medical advice. This podcast including Ben Azadi disclaim responsibility from any possible adverse effects from the use of information contained herein. Opinions of guests are their own, and this podcast does not accept responsibility of statements made by guests. This podcast does not make any representations or warranties about guests qualifications or credibility. Individuals on this podcast may have a direct or non-direct interest in products or services referred to herein. If you think you have a medical problem, consult a licensed physician.
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