S2E1: A Conversation with the Broad Institute's Anne Carpenter
Theory and Practice
The Neuroscience of Mental Illness in Skin Cells
The only way you can typically get brain cells is on the off chance that someone happens to have cancer and they get a biopsy. But generally speaking, people aren't willing to give them up. So this entire series of experiments was done on fibroblasts, which are skin cells. And it turns out that it actually is quite sensible. Once we found the mitochondrial phenotype, it sort of fit with a lot that is known.
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