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Ketamine: Benefits and Risks for Depression, PTSD & Neuroplasticity
Huberman Lab
The Neuroscience of Ketamine
We know that certain neural circuits change when people take ketamine in these patterns of dosage and frequency. And again, that's the injected form twice per week, over three weeks, and then they get some durable resistance to depression. We've completely neglected, meaning I've completely neglected until now, what bridges those two levels of understanding? What bridges those twolevels of understanding are the neural circuits that actually change when one takes ketamine. Whether or not those changes occur quickly, whether or not they involve an MDA receptors or the opioid receptor systems or both.
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