Comparing Exercise and Education Programs with Placebo for Knee Osteoarthritis

The chapter delves into a study comparing the efficacy of exercise and education programs with an open-label placebo (saline injections) for knee osteoarthritis, highlighting details of the trial design, outcomes, and potential placebo effects. The hosts discuss the DISCO trial, emphasizing its open-access nature, predictions on outcomes, and the skepticism within Danish culture. The researchers suggest that any intervention is more effective than doing nothing for osteoarthritis, showcasing the importance of active treatment approaches.