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51. Gout

ACR on Air

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The Evolution of Gout

Gout is primarily a disease of urate excretion through the gut and also the kidneys. The pathways that are most associated with both hypo-uracemia and Gout are not pure in metabolism pathways. They're actually renal urate transporters and gut urateTransporters. And so our environment has an impact on that. We know that higher BMI, for example, will also influence urate transport within the kidney.

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