This chapter explores the issues of reproducibility and research integrity in medicine. It discusses the UK parliamentary report suggesting timely publication of corrections, the lack of correction in systematic reviews, and the need for improved oversight and checks. It also mentions the efforts by Egyptian authorities to enhance governance of trials.
Investigations suggest that, in some fields, at least one-quarter of clinical trials might be problematic or even entirely made up. Faked or unreliable trials are dangerous, as they could end up being included in the reviews that help inform clinical treatments. However, the extent of the problem in unclear, and many researchers urge stronger scrutiny.
This is an audio version of our Feature: Medicine is plagued by untrustworthy clinical trials. How many studies are faked or flawed?
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