85 - NephMadness 2024
The Curious Clinicians
Understanding Urine Anion Gap and Kidney Function
The chapter covers the concept of urine anion gap as a surrogate test for measuring urinary ammonium levels to indicate kidney function in response to acidosis. It explains the generation and excretion of ammonium through the nephron and discusses the implications of urine anion gap in diagnosing renal tubular acidosis and acid-base disorders, highlighting limitations in reflecting osmolarity due to the presence of other anions like lactic acid and ketones.
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