The Fellow on Call: The Heme/Onc Podcast cover image

Episode 060: Heme Consults Series - Fundamentals of Transfusion Medicine

The Fellow on Call: The Heme/Onc Podcast

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The Importance of Cross Matching Blood

Sugar is attached to like proteins, sugar chains, gligo proteins. If you have a heavily transfused patients like a sickle patient or a thalassemia patient, they may have a positive antibody screen because they've been exposed to so much. That's called aloe immunization. Cross matching can be done electronically to say what's going to be compatible if that antibody screen is negative. And if the antibody screen is positive, you are manually mixing blood together in a test tube to make sure that there is no reaction when I'm going to give this blood to this patient.

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