4min chapter

The Carlat Psychiatry Podcast cover image

MDMA: What Went Wrong Part 2

The Carlat Psychiatry Podcast

CHAPTER

Issues and Methodologies in MDMA Clinical Trials

This chapter delves into potential issues in MDMA clinical trials like therapist suggestions, functional unblinding, and active comparators, comparing trial methodologies with psychoactive placebos in ketamine trials. It also covers recruitment biases from individuals with prior positive MDMA experiences and concerns of expectancy bias among researchers advocating for psychedelics.

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