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The History of the Semmelweis Doctrine
Semmelweis died from an infection following violent beatings by the asylum staff while trying to restrain him. Joseph Lister came across a series of papers by Louis Pasteur and began to study under the microscope, the puffs from amputation wounds. The next big milestone came in 1935 with the development of the sulfonamide prontazole which greatly reduced mortality due to puperal fever.