#117: Dom D'Agostino on Fasting, Ketosis, and The End of Cancer
The Tim Ferriss Show
Cancer Cells Use Glycose for Energy
Cancer cells in a kind of default to a metabolic penotype called the warberg a fact rit. They derive most of their energy from glucose metabolism and their biosynthetic processes. As as the tumor grows, it's using glucos for energy, but its also using glucose to expand the bio mass of the tumor. So cancer cells can use glucose, primarily glucose btthey can also use glutomine and thers.
Dr. Dominic “Dom" D’Agostino (@DominicDAgosti2) is an Assistant Professor in the Department of Molecular Pharmacology and Physiology at the University of South Florida Morsani College of Medicine, and a Senior Research Scientist at the Institute for Human and Machine Cognition (IHMC). He has also deadlifted 500 pounds for 10 reps after a seven-day fast. He’s a beast and — no big surprise — he’s a good buddy of Dr. Peter Attia, my MD friend who drinks "jet fuel" in search of optimal athletic performance. The primary focus of Dom's laboratory is developing and testing metabolic therapies, including ketogenic diets, ketone esters and ketone supplements to induce nutritional/therapeutic ketosis. D’Agostino’s laboratory uses in vivo and in vitro techniques to understand the physiological, cellular and molecular mechanism of metabolic therapies and nutritional strategies for peak performance and resilience. His research is supported by the Office of Naval Research (ONR), Department of Defense (DoD), private organizations and foundations. Show notes and links for this episode can be found at www.fourhourworkweek.com/podcast. This podcast is brought to you by Audible. I have used Audible for years and I love audio books. I have 2 to recommend: The Graveyard Book by Niel Gaiman Vagabonding by Rolf Potts All you need to do to get your free audiobook and a free 30-day trial is go to Audible.com/tim. Choose one of the above books, or choose between more than 180,000 audio programs. That could be a book, a newspaper, a magazine or even a class. It's that easy. Go to Audible.com/Tim and get started today. Enjoy! This podcast is also brought to you by 99Designs, the world’s largest marketplace of graphic designers. I have used them for years to create some amazing designs. When your business needs a logo, website design, business card, or anything you can imagine, check out 99Designs. I used them to rapid prototype the cover for The 4-Hour Body, and I've also had them help with display advertising and illustrations. If you want a more personalized approach, I recommend their 1-on-1 service, which is non-spec. You get original designs from designers around the world. The best part? You provide your feedback, and then you end up with a product that you're happy with or your money back. Click this link and get a free $99 upgrade. Give it a test run… Enjoy!
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