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Rethinking Pain: A Fresh Perspective on the Biopsychosocial Model and the Future of Biological Treatments

The Modern Pain Podcast

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The Noceceptive System and Pain

In the last 20 years, we've come a great deal to a great deal of understanding that no ciception is not the way we defined it. If you look at the ISP website, it's defined as the activation of peripheral noceceptors. We can have glial cell activation in our brain in the areas of second and third order neurons. And if those glial cells get activated, they change the thresholds and they can upregulate or dysregulate or downregulate some neurons in our brain. This can be translated into like a pain state. Now it's, and again, it's not a mind thing. It's a bio thing. The best construct that

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