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Opioid poisonings: shortfalls in treatment and new threats

CMAJ Podcasts

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Xylazine: A New Challenge in the Opioid Crisis

This chapter examines the rise of the veterinary sedative xylazine in street drugs, especially in combination with fentanyl, and its pharmacological implications. It highlights the clinical challenges healthcare providers face when treating opioid overdoses complicated by xylazine use, stressing the importance of continued standard care. The discussion urges a balanced perspective on the risks posed by xylazine in the context of the ongoing opioid epidemic.

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