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Chapter Ten : Acid-Base Physiology

Channel Your Enthusiasm

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Is Bicarbonate a Good Solution to Acidosis?

There's a lack of clinical evidence for improved outcomes with giving bicarbonate. Despite we've been doing it for 100 years people don't get better when you fix their acidosis. The ability of bone to buffer hydrogen is essentially infinite given the mass of the bones compared to the acid levels that we're talking about. When you have distal renal to your acidosis every day you're in a positive hydrantine balance. Every day whether it's mild or severe every day you are consuming more bicarb than you're making new bicarb. So you would think at some point you would run on a bicarb but you don't because it's when you get to

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