CTDNA and Colorectal Cancer

For the first time we see this novel approach of activating T cells on a different way not through the canonical activation by binding the antigen to the TCR here is like a direct activation of the T cell and we are getting for the first time a result in a solid tumor that is really attractive some 23% of here of our patients that were relapsing patients many of them were actually in third line. The safety profile was reasonable there were some the cytokine release syndrome in half of the patients but typically grade one or two only one patient grade three.