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Understanding Minimal Residual Disease (MRD) in Myeloma Treatment
The chapter explores the complexities of measuring minimal residual disease (MRD) in myeloma and its significance in treatment decisions. It discusses the debate around using MRD negativity as a primary treatment goal, its limitations as a predictor of overall survival, and its potential impact on accelerating drug approvals. The speakers also analyze the challenges and considerations in aiming for MRD negativity, including the balance between treatment outcomes, patient care, and clinical trial standards.